News for Healthier Living

Precision STING delivery could help convert immune-desert tumors into inflamed tumors

A new review highlights the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway as a central switch that can convert immunologically "cold" tumors into "hot," inflamed tumors and improve immunotherapy responses. The authors synthesize how acute activation of this innate immune sensor promotes antigen presentation, T-cell priming, and type I interferon (IFN-I) signaling, while chronic or mistimed activation can drive immunosuppression, metastasis, and treatment resistance. The review maps next-generation STING-targeted agonists and delivery platforms--including antibody-drug conjugates (ADCs), immune-stimulating antibody conjugates (ISACs), nanoparticles, bacterial vectors, and exosomes--to distinct tumor microenvironment (TME) phenotypes. It proposes a strategic framework for rational combination therapies and biomarker-driven patient selection.

October 16, 2026

October 29 2026

• Specialized Immune Cells Help Our Skin Respond to Changing Environmental Conditions
• Platelets May Play an Unexpected Role in Glioblastoma Progression
• Spinal Cord Injury Reshapes Gut Microbes That Influence Whole-Body Health
• Reversing Radiation-Activated Immune Suppression in Cancer
• Permanent Daylight Saving Time could lead to at least 2B more dark commutes to school for US children
• How a New Brain Procedure Gave Parkinson's Tremor Patient Back the Hobby He Loves
• Why Some Patients Quit a Newer Insomnia Medication
• 40-Year Mystery Solved: Common Gut Virus Infects Bacteria, Not Human Cells
• New Research Explores Why Some People Struggle More with Mental Health After Giving Birth
• Activating Cancer-Fighting Protein Could Make T-Cell Immunotherapies More Effective, Study Finds
• Hertz Fellow Becca Carlson Uses AI to Identify New Drug Targets on Human Cells
• Study Identifies Translation Regulation Mechanisms Involved in Cancer Development and Treatment Resistance
• RWJBarnabas Health Raises Awareness of Stroke Warning Signs and Importance of Early Intervention This World Stroke Day
• GW Is a Founding Partner in Hugging Face's Project ProtoStar, a National Effort to Make Publicly Funded Science AI-Ready
• GW Public Health Experts Call for Greater Investment in Preventing Zoonotic Diseases Amid Climate Change and Global Health Funding Shifts
• Immune System Protein Is a Cancer Killer on Its Own, New Study Shows
• Genetic Testing May Help Identify Inherited Blood Disorder Carrier Status Earlier
• A New Contrast Agent That Detects Cardiac Fibrosis and Slows Its Progression
• New Transport Pathway Shows Promise for Brain Drug Delivery
• Study reveals distinct cellular and genetic differences in colorectal cancer in younger patients
• Newly Discovered Pathway Fuels Production of Cancer-Driving Proteins
• Zurich Blue, a nano-pigment inspired by an ancient prototype

October 28 2026

• Lung Cancer Awareness Month Tipsheet; Resources for Smoking Cessation, Early Screening -- and New Research and Treatments Against Deadly Disease
• Researchers Identify Pathway That Enables Regulatory T Cells to Prevent Devastating Autoimmune Responses to Gut Bacteria
• Wider Surgical Margins May Not Mean Better Cancer Control, Finds Large-Scale Treatment Trial
• Robot Could Improve Diagnosis, Treatment of Small Intestine Disorders
• What Might Contribute to Burnout Experienced by College Athletes?
• Mutated Immune Cells Raise Red Flags in Lupus
• Mayo Clinic Study Finds Measurable Brain Response Within Minutes of Deep Brain Stimulation in Patients with Epilepsy
• New Microscopy Platform Enables Imaging of Neuronal Activity at Single-Cell Resolution at Unprecedented Tissue Depth
• Kids, Mosquito Bites, and West Nile Virus: Guide for Caregivers
• Cedars-Sinai's Quit Alliance Helps LGBTQIA+ Community Stop Using Tobacco
• The Medical Minute: Newborn intensive care: What parents need to know
• 'Once Enamel Is Gone, It Can't Be Replaced'
• Health Scare Pushes Ritchie Into Advocacy for Blood Donation
• Ohio State First in Midwest to Use Novel Device to Treat Heart Rhythm Disorder
• Video Available: Interview Prep and Media Training for Experts - Best Practices Webinar
• Living Near Water-Pollution Sources Associated with Rare Brain Disorder
• Intersection of Pop Culture, Fandom, and STEM Engagement: Virtual Expert Panel
• Research Reveals How the Heart's Unusual Carbohydrate Metabolism Helps It Stay Strong
• Abnormal Neurons Are Common in the Developing Brain. The Body Has a Mechanism to Eliminate Them
• Mindfulness-Based Therapy May Change Brain Responses to Drug Cues in People With Opioid Use Disorder, Mount Sinai Study Finds
• Public Health Leaders and Scholars File Amicus Brief Challenging CMS Medicaid Work Requirement Rule in Taylor v. Kennedy
• Combining 2 VEGF-Blocking Targeted Therapies Significantly Boosted Survival in Kidney Cancer Study
• Could a Diabetes Medication Be the Next Wonder Drug?
• Topography Emerges as the Leading Land-Surface Control on CYGNSS GNSS-R Coherence Across the Tropics
• Animal and plant proteins show different associations with testosterone levels in men
• Chinese Neurosurgical Journal Review Explores Neurological Considerations for Gender Dysphoria Care
• How to Measure Meaningful Benefit for Patients With Rare Diseases

October 27 2026

• Sara J. Finley to succeed Edie Carell Johnson as Chair of Vanderbilt Health Board of Directors
• Brachytherapy: 6 Common Questions About Focused Radiation Therapy
• Children's Hospital Los Angeles and Partner CIELO Awarded $1.69 Million Research Grant to Expand Precision Medicine for Indigenous and Hispanic Children
• Roswell Park Researchers Identify Critical Window for Boosting Immunotherapy Response in Prostate Cancer
• How Sex-Based Biology Shapes the Brain's Response to Injury
• Rising Rates of Colorectal Cancer Found in Nearly All Age Groups
• UK HealthCare Patient Among First in US to Receive Experimental Lupus Treatment
• ASTRO Updates Guideline on Shorter-Course Radiation Therapy for Localized Prostate Cancer
• New Clues About Why the Eye's Iris Sheds in Pigmentary Glaucoma
• Research Reveals Small Brain Area Has a Giant Role in Memory
• Baltimore Cancer Patients Turn to Acupuncture for Pain Relief at Medi-Spa
• Researchers Tie Exposure to Wildfire Smoke During Pregnancy to Higher Risk of Autism
• Marathon Season is Here! Tips for a Safe Running Program
• Living Alone Linked to Mortality Risk From Multiple Causes in U.S. Including Cancer; Suicide Highest
• Avian Influenza Threatens Vulture Populations Worldwide
• More Saturated Fat Produced Unexpected Changes in the Blood
• ISPOR Launches Its First Interpretive Report on the HARPER Template
• Why a Breakthrough Blood Cancer Drug Could Be Better for Patients

October 26 2026

• Women's Heart Health Care Starts at Puberty: New Shared Framework from Leading Medical Societies
• 'Here. For L.A.': Cedars-Sinai Community Teams Bring Flu Vaccinations Closer to Home
• High Dose Oxytocin Protocol Linked to Lower Postpartum Hemorrhage Rates
• Perioperative Apalutamide in High-Risk Localized or Locally Advanced Prostate Cancer Substudy Supports Reduced Risk of Metastasis and Death
• Mayo Clinic Study Explores Cerebrospinal Fluid DNA Testing When Brain Tumor Diagnosis Is Uncertain
• AI Medical Scribe Cuts Clinician Documentation Time, with Greater Reduction Among More Frequent Users
• Obesity in Young Adults Associated with Higher Risk for Early-Onset Cancer
• Minimally Invasive Liver Surgery for Colorectal Liver Metastasis Reduces Complications Without Affecting Long-Term Cancer Outcomes
• Nearly 9 in 10 Organizations Oppose Proposed OMB Federal Grant Rule Changes
• Deficits in a Mouse Model of Autism-Related Neurodevelopmental Disorder and Discover that Early-Life Exercise Intervention Can Improve Motor Outcomes
• Women's Heart Health Care Starts at Puberty: New Shared Framework from Leading Medical Societies
• Dr. Frank Liporace Honored by the Arthritis Foundation of New Jersey as 2026 Orthopedic Champion Honoree
• Virtual Briefing: ASN Kidney Week 2026
• Breast Cancer Care Falls Short for Black Patients and People with a Learning Disability, Warns First-of-Its-Kind UK Study
• Heart Drug Combo Reduces Kidney Damage in Septic Shock Surgery, Major Trial Finds
• How the Brain Holds Information in Mind
• Aston University-Led International Study Finds ADHD Medication Unlikely to Raise Risk of Self-Harm
• Pancreatic Cancer: Researchers Reprogram the Tumor Microenvironment
• Immunotherapy combo extends survival for patients with aggressive small cell lung cancer, based on trial results presented by Dana-Farber at ESMO Congress 2026
• Friends May Help Drive Regular Cancer Screening, SMU study finds
• ESMO 2026: UT MD Anderson Highlights Innovative Approaches to Monitor, Prevent and Treat Cancer

October 25 2026

• ESMO 2026: New Targeted Therapy Improved Survival for Patients with KRAS-Mutated Lung Cancer

October 24 2026

• Advanced Age Does Not Limit the Benefits of Sodium-Glucose Cotransporter 2 Inhibitors in Chronic Kidney Disease
• A Third of Young Adults Turn to Artificial Intelligence for Substance-Use Information
• ESMO 2026: Immunotherapy Combination Extends Survival in Advanced Endometrial Cancer

October 23 2026

• What does voter suppression have to do with health?
• Reproductive Health and Cystic Fibrosis: New Guidance Offers Options and Hope
• Suicide Attempts, Ideation Spiked Significantly Among Older U.S. Adults After COVID-19 Pandemic
• Experts Share Updates on Breast Cancer Screening and Treatment
• Investigational Vaccine Generates Immune Response to KRAS Mutations in Pancreatic Cancer Study
• Phase 2 BESTOW Trial Generates Promising Kidney Function and Quality of Life Results for Tegoprubart Versus Tacrolimus Immunosuppression in Kidney Transplant Recipients
• Standard Kidney Function Tests Underestimate Chronic Kidney Disease in People with Cancer
• US-Mexico Border Counties Face High Kidney Disease -Related Mortality and Low Nephrologist Availability
• Study Reveals Amino Acid Can Diminish Age-Related Inflammation
• Mindfulness in DNP Education: Cultivating Resilience and Leadership in Advanced Practice
• Late Breaking, High-Impact Clinical Trials Featured at Kidney Week 2026 Explore New Frontiers to Improve Kidney Health
• JMIR News: GLP-1 Ads' Effects on Body Image; AI Initiatives for CPR and Gender-Based Violence Screening; Patient Perspectives; and Catching Postpartum Psychosis Early
• Johns Hopkins APL Technology Targets Earlier Stress-Fracture Detection
• ESMO: New Analysis Reinforces Survival Benefits of Targeted Therapy for Advanced Pancreatic Cancer
• Online Resources and Coaching Helped People Seek Genetic Testing for Cancer
• What makes you, you? Massive Study Maps the Genetics of Personality
• Scientists Propose National Microbiome Plan to Prevent Chronic Disease
• Pancreatic Cancer: Researchers Reprogram the Tumor Microenvironment
• Chinese Neurosurgical Journal Study on Agitation Management After Traumatic Brain Injury
• Aston University-Led International Study Finds ADHD Medication Unlikely to Raise Risk of Self-Harm
• UMA Scientists Reveal How Climate Studies Could Predict Where and When the Risk of Ebola Outbreaks Increases
• From Football to Futbol, Rams and Angel City FC Visit Cedars-Sinai
• AI Improves Diabetes Care One Decision at a Time
• Hackensack Meridian Jersey Shore University Medical Center Chair of Neurology's Research Accelerating, Enhancing Emergency Stroke Care
• Study Finds Stress During Pregnancy May Change Signals From the Placenta Tied to Fetal Brain Development
• AI Tool May Support Dermatologists in Assessing Skin Lesions for Cancer Risk

October 22 2026

• 'Smart Bomb' Combination Attacks Triple-Negative Breast Cancer in Preclinical Study
• Prostate Cancer Drug Shows Promise in New Clinical Trial
• Yale Researchers Improve RNA Extraction From Precision-Cut Lung Slices
• Lipscomb University Faculty Make History as First Certified Anesthesiologist Assistants to Manage Surgical Cases in Tennessee
• An Italian Day in Philadelphia: Science, Medicine and a Transatlantic Bridge
• Social Determinants of Health Linked with Kidney Failure Risk Among Survivors of Critical Illness and Acute Kidney Injury
• Potassium Binder May Ease the Burden of Dietary Potassium Restriction in People on Dialysis
• Fruits and Vegetables Outperform Medication for Treating Metabolic Acidosis in Chronic Kidney Disease
• Standardized Kidney Biopsy Protocol Is Safe in High-Risk Patients
• Clinical Support Tool Helps Primary Care Health Professionals Detect and Treat Chronic Kidney Disease
• Adding Emotion Management Skills to Family Weight Treatment May Help Teens Maintain Weight Loss
• Excessive Weight Gain During Pregnancy Linked to Higher Risk of Severe Maternal Complications
• Developing a New Vaccine and Therapies to Fight Lyme Disease
• High-Impact Clinical Trials Generate Promising Results for Improving Kidney Health
• Imaging Studies Reveal How Particle Size Affects Therapeutic Delivery to the Brain and Brain Tumors
• Before the Doorbell Rings: RWJBarnabas Health Shares Tips to Prepare Children with Sensory Sensitivities for Halloween
• Male Breast Cancer: Risk Rises with Age, Mayo Clinic Expert Explains
• Comprehensive DNA Sequencing Reveals Hidden Drivers of Cancer
• 'Molecular Glue' Stabilizes Protein That Inhibits Development of Non-Small Cell Lung Cancer and Uterine Cancer
• Vanderbilt Health-led team maps gene variants that can cause sudden death
• Hands-on Training May Help Pediatric Residents Communicate Better with Families of Medically Complex Children
• International Study Helps Support FDA Approval of HIV Drug for Newborns

October 21 2026

• UCLA Health-Led Study Finds NYC Tenant Right-to-Counsel Program Linked to Fewer ED Visits in High-Risk Neighborhoods
• FSU developing statewide data system to improve mental healthcare in Florida
• Nearly Half of On-Duty Firefighter Deaths Are Heart Related
• UM School of Medicine's Andreea Creanga Elected as Member of Prestigious National Academy of Medicine
• Perinatal Depression Program Cuts Risk by Double Digits
• FSU Study Finds Healthcare Provider Photos in Waiting Rooms Can Strengthen Patient Trust
• LSD Does More Than Desynchronize the Brain
• Children's Hospital Los Angeles Offers Inspire Device to Treat Obstructive Sleep Apnea in Teens With Down Syndrome
• Laboratory Study Shows Needle-Free mRNA Vaccine Protects Against COVID and Flu
• A 'Game Changer' for Severe Depression That Cuts Treatment Time in Half
• New AI Platform Helps Uncover Promising Cancer Drug Combinations
• Half-Matched Bone Marrow Transplant Expands Treatment Options for Children and Young Adults with Severe Aplastic Anemia
• The Medical Minute: The Link Between Obesity and Breast Cancer Recurrence
• Study Examines Stroke Prevention for People with AFib After Brain Bleeds
• After Stroke and AFib, Restoring Heart Rhythm Linked to Lower Risk of Another Stroke
• Study Advances Mechanistic Insight into Tuberculosis Vaccine's Link to Reduced Dementia Risk
• Build-Up of Common Enzyme Stunts Brain Growth
• Physical Activity After Cancer Diagnosis Linked to Lower Healthcare Costs Among Older Survivors, New Study Finds
• Mayo Clinic First to Study Low-Dose Radiation for Parkinson's Disease
• Can Exercise Slow Parkinson's Decline?
• Mount Sinai to Lead National Trial of Targeted Therapy for Infants With Noonan Syndrome and Severe Hypertrophic Cardiomyopathy
• New Optogenetic Tool Inhibits Neurons and Heart Muscle Cells
• Hidden Proteotoxic Cargo May Undermine Stem Cell Therapy Success
• Like Humans, Some Primates Become Cautious of Germs in the Wake of a Viral Outbreak

October 20 2026

• How to Control Ferromagnetism Using Light
• New Method for Guaranteed Stability and Improved Performance for Robots on the Move
• Cranberry Juice May Be a Boon for Oral Hygiene
• Dana-Farber Presents Phase 3 Lung Cancer Data in ESMO Presidential Symposium
• Researchers Unlock Promising Lung Cancer Treatment Option
• Water As We've Never Known It: Physicists Test Water Beyond Earth-like Conditions
• New Approach Gauges Reliability of AI Breast Cancer Diagnosis
• Children's Hospital Los Angeles Is First Pediatric Hospital on West Coast to Implant Novel Spring Rod System for Early Onset Scoliosis
• Sensory Overload Reported by 60% of U.S. Parents, Lurie Children's Study Finds
• A Woman's Journey to Lifelong Bone Health
• High-Nicotine E-Cigarettes Linked to Rising Nicotine Dependence Among Young Adults
• Artificial Intelligence-Enabled Triage Tools May Reflect Human Biases
• Texas Football Player Back on the Field After Rare Knee Condition Nearly Ended His Career
• How L-Carnitine, Found in Red Meat and Exercise Supplements, May Amplify Inflammation
• A Streak of Good Fortune After Type A Aortic Dissection
• Spur Ventures Strengthens Nebraska's Ag Tech Ecosystem
• Parents of Transgender Youth Faced Mental Health Declines After the 2025 U.S. Presidential Inauguration
• Can better gut health help patients with ovarian cancer tolerate chemotherapy?
• First Joint Guidelines of Care for Hidradenitis Suppurativa Issued by American Academy of Dermatology and Hidradenitis Suppurativa Foundation
• Nutritional Supplement May Help Ease 'Brain Fog' After Breast Cancer Treatment
• Body Composition Changes on CT Scans May Help Identify Pancreatic Cancer Risk
• The AI Is Listening: Implications of Machine Generated Clinical Notes on Health Care
• New Biological Model Proposes Why Postpartum Vulvar Pain Persists After Hormones Recover
• Study Finds Air Purifiers Do Not Reduce Surgical Infection Risk
• New Advances in the Explanation of the Most Common Chronic Liver Disease
• Migraine, Endometriosis Overlap Far More Than Recognized, Analysis of 13 Million Finds
• As Science and Technology Advance, Nurses Become More Essential to Successful Organ Transplants
• How Rutgers Is Training Tomorrow's Public Health Heroes

October 19 2026

• Moffitt Researchers Find Ways to Improve How a T Cell Fights Cancer
• Now Peer-Reviewed: Journal of Cosmetic Dermatology Publishes Study Validating Sente's Heparan Sulfate + Vitamin C Pairing, Including a 44% Drop in a Key Oxidative Stress Marker in 24 Hours
• Protecting Young Skin: A New Approach to Melanoma Prevention for Children
• RWJBarnabas Health Honored with New Jersey Business Magazine's Community Service Award
• ADLM Opposes CMS Proposal to Eliminate Board Certification for High-Complexity Laboratory Directors
• Common Pregnancy Symptoms Reveal Stage 3 Colon Cancer
• The Race to Predict and Prevent Sudden Cardiac Arrest
• AI Model Can Uncover Unseen Health Issues in CT Scans
• Children's Hospital Los Angeles Team Discovers Key Pathway in Heart Lymphatic Vessel Development
• National Academy of Medicine welcomes 3 new UCLA faculty members
• Researchers Harness the Heart's Natural Defense Against Heart Attack Damage
• Proposed Changes to Hepatitis B Vaccination Schedule Could Significantly Increase Infections, Model Suggests
• 1 in 6 Adults with Type 1 Diabetes Report Moderate to Severe Depression or Anxiety Symptoms
• AI Models Rarely Recommend Unnecessary Care in Choosing Wisely Tests
• Cardiovascular Diagnoses During Medicare Home Assessments Rise Yet Follow-Up Care Lacking
• History Is Made: Missouri Allows Counselors to Practice Across State Lines
• Year-Long Fitness Tracker Data May Offer Clues About Future Brain Health, Study Suggests
• To Fuse, Cells Block Their Repair System
• Millions of Older Australians Exposed to Overlapping Medication Risks
• New Microscopy: Seeing the Brain Like Never Before
• 4 in 5 Parents Say Having a Baby Is Too Expensive

October 18 2026

• Greener anesthesia cuts operating room emissions in half, slashes anesthetic costs nearly 40%
• Smoking or vaping cannabis, but not edibles, linked to need for more anesthesia during upper endoscopy, study suggests
• Melatonin and Ambien before surgery may improve sleep, reduce pain and opioid use after surgery
• Could staying active before surgery help prevent postoperative delirium?
• Cannabis use linked to higher heart attack risk during and after surgery, but fewer blood clots
• GLP-1 drugs linked to lower risk of serious heart-related complications and infections after surgery
• Certain Anti-Epileptic Drugs May Take Toll on Bone Health Yet Vitamin D Supplementation is Low: Real-World Analysis

October 17 2026

• Mobile app monitoring may reduce serious complications after surgery, new study finds
• Ketamine during or after C-sections may ease early postpartum depression symptoms, new study suggests
• Wearing headphones during surgery may reduce nausea and vomiting afterward
• Language barriers may affect access to standard treatment for headaches after epidurals for new moms

October 16 2026

• Can Changing the Circadian Rhythm of Teen 'Night Owls' Improve Depression Outcomes?
• NSF-Funded Research Aims to Make AI a More Reliable Tool for Heart Testing
• Having Insurance Doesn't Mean You Can Get a Mental Health Appointment
• A 'Huge Leap Forward' for Brain Injury Care in First Responders
• Finding Their Sense of Direction: Cell Movement Helps Tissues Establish Polarity
• The Weekly Dose: Kidney disease; diet changes; brain pressure
• AMCP Market Insights Findings Show Uncertainty in Biomarker Testing for ESR1-Mutated Advanced Breast Cancer as Payers Weigh Earlier Detection and a Growing Class of Targeted Therapies
• JMIR News: Informed Consent's Redesign for AI-Related Trials, an Autonomous Oxygenation Device, and the Physician-Led Campaign for Canada's Safe Social Media Act
• Structurally guided therapy shows promise for patients with specific EGFR-mutated lung cancer in Phase 1b trial
• Phosphorylation Switch Helps Grapevines Weather Freezing
• Patient-Centered Financial Navigation Assistance Helps Reduce Financial Toxicity Among Cancer Patients, UNC Study Finds
• Precision STING delivery could help convert immune-desert tumors into inflamed tumors
• The Receptor Behind Chili-Pepper Burn May Hold Clues to Pain Treatments